Lee Winston Jones, PhD

Associate Professor of Radiation Oncology
Associate Professor of Pathology
Associate Professor in Psychiatry and Behavioral Sciences

Department
Radiation Oncology

Address:
Box 3085 Med Ctr
Durham, NC 27710

Office Telephone:
(919) 668-6791

Training:

• PhD, University of Alberta, 2002

Research Interests:
Dr. Jones"s research program focuses on a translational approach to: (1) evaluate the cardiovascular / functional impact of cancer therapy, and efficacy of defined exercise training to prevent and/or treat dysfunction, and (2) elucidate the effects, and underlying systemic and molecular mechanisms, of defined aerobic training on tumor progression and metastatic dissemination. He has published numerous scientific articles and book chapters. He is also a member of the International Editorial Board for Lancet Oncology. His research program is supported by the National Institutes of Health, American Cancer Society, and U.S. Department of Defense Breast Cancer Research Program.

Publications:

• Betof, AS; Dewhirst, MW; Jones, LW. Effects and potential mechanisms of exercise training on cancer progression: a translational perspective. Brain, Behavior, and Immunity. 2013;30 Suppl:S75-S87. Abstract
  
  
• Jones, LW; Antonelli, J; Masko, EM; Broadwater, G; Lascola, CD; Fels, D; Dewhirst, MW; Dyck, JR; Nagendran, J; Flores, CT; Betof, AS; Nelson, ER; Pollak, M; Dash, RC; Young, ME; Freedland, SJ. Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer. Journal of Applied Physiology. 2012;113:263-272. Abstract
  
  
• Jones, LW; Courneya, KS; Mackey, JR; Muss, HB; Pituskin, EN; Scott, JM; Hornsby, WE; Coan, AD; Herndon, JE; Douglas, PS; Haykowsky, M. Cardiopulmonary function and age-related decline across the breast cancer survivorship continuum. Journal of Clinical Oncology. 2012;30:2530-2537. Abstract
  
  
• Koelwyn, GJ; Khouri, M; Mackey, JR; Douglas, PS; Jones, LW. Running on empty: cardiovascular reserve capacity and late effects of therapy in cancer survivorship. Journal of Clinical Oncology. 2012;30:4458-4461. Abstract
  
  
• Lakoski, SG; Eves, ND; Douglas, PS; Jones, LW. Exercise rehabilitation in patients with cancer. Nature Reviews. Clinical Oncology. 2012;9:288-296. Abstract
  
  
• Jones, LW; Liang, Y; Pituskin, EN; Battaglini, CL; Scott, JM; Hornsby, WE; Haykowsky, M. Effect of exercise training on peak oxygen consumption in patients with cancer: a meta-analysis. The Oncologist. 2011;16:112-120. Abstract
  
  
• Scott, JM; Khakoo, A; Mackey, JR; Haykowsky, MJ; Douglas, PS; Jones, LW. Modulation of anthracycline-induced cardiotoxicity by aerobic exercise in breast cancer: current evidence and underlying mechanisms. Circulation. 2011;124:642-650. Abstract
  
  
• Jones, LW; Douglas, PS; Eves, ND; Marcom, PK; Kraus, WE; Herndon, JE; Inman, BA; Allen, JD; Peppercorn, J. Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer. BMC Cancer. 2010;10:531. Abstract
  
  
• Jones, LW; Eves, ND; Kraus, WE; Potti, A; Crawford, J; Blumenthal, JA; Peterson, BL; Douglas, PS. The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design. BMC Cancer. 2010;10:155. Abstract
  
  
• Jones, LW; Eves, ND; Peppercorn, J. Pre-exercise screening and prescription guidelines for cancer patients. Lancet Oncology. 2010;11:914-916. Abstract
  
  
• Jones, LW; Peppercorn, J. Exercise research: early promise warrants further investment. Lancet Oncology. 2010;11:408-410. Abstract
  
  
• Jones, LW; Watson, D; Herndon, JE; Eves, ND; Haithcock, BE; Loewen, G; Kohman, L. Peak oxygen consumption and long-term all-cause mortality in nonsmall cell lung cancer. Cancer. 2010;116:4825-4832. Abstract
  
  
• Haykowsky, MJ; Mackey, JR; Thompson, RB; Jones, LW; Paterson, DI. Adjuvant trastuzumab induces ventricular remodeling despite aerobic exercise training. Clinical Cancer Research. 2009;15:4963-4967. Abstract