For most medical students, gross anatomy is an early first-year course taken before significant clinical experience is obtained. Over the ensuing years of medical school and residency, much of this knowledge is lost as it may not be routinely applied during clinical practice. It is important that medical trainees in radiation oncology and other anatomy-dependent disciplines again become students of anatomy, as the successful practice of such disciplines requires in-depth understanding of anatomical principles. To fulfill this need, in 2005 the Department of Radiation Oncology at Duke University Medical Center began hosting a series of oncoanatomy classes. Each session explores specific anatomical sites and the types of tumors likely to affect them. Oncoanatomy classes include a didactic component, including presentations and treatment planning applications, and a laboratory component with cadaver dissections presented by anatomists. Beginning in 2008, video recordings of the oncoanatomy classes will be made available on the Internet to benefit medical trainees in all disciplines.