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Brian Gary Czito, MD

Professor of Radiation Oncology
Office: 05145B Morris Clinic, Durham, NC 27710
Campus Mail: DUMC Box 3085 Med Ctr, Durham, NC 27710

Listed in Best Doctors in America. Listed in Top Doctors in North Carolina. His research interests include gastrointestinal malignancies, including treatment and integration of novel systemic agents with radiation therapy in the treatment of esophageal, gastric, hepatobiliary, pancreatic, colorectal and anal malignancies; phase I/II clinical trials evaluating novel systemic/targeted agents in conjunction with radiation therapy; investigation and optimization of the treatment of gastrointestinal malignancies, with focus on the above tumor sites.

Education and Training

  • American Board of Radiology (ABR), American Board of Radiology, 2001 - 2021
  • Chief Resident, Massachusetts General Hospital, 2000 - 2001
  • Resident, Massachusetts General Hospital, 1997 - 2000
  • Intern, St. Joseph Mercy Health Systems, 1996 - 1997
  • M.D., Medical College of Georgia School of Medicine, 1996

Publications

Zhang, Jiahan, Chunhao Wang, Yang Sheng, Manisha Palta, Brian Czito, Christopher Willett, Jiang Zhang, et al. “An Interpretable Planning Bot for Pancreas Stereotactic Body Radiation Therapy.” Int J Radiat Oncol Biol Phys 109, no. 4 (March 15, 2021): 1076–85. https://doi.org/10.1016/j.ijrobp.2020.10.019.

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Salama, April K. S., Manisha Palta, Christel N. Rushing, M Angelica Selim, Kristen N. Linney, Brian G. Czito, David S. Yoo, et al. “Ipilimumab and Radiation in Patients with High-risk Resected or Regionally Advanced Melanoma.” Clin Cancer Res 27, no. 5 (March 1, 2021): 1287–95. https://doi.org/10.1158/1078-0432.CCR-20-2452.

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Czito, Brian, and Claus Rödel. “Emerging Treatment Paradigms in Localized Rectal Cancer.” Pract Radiat Oncol 11, no. 1 (January 2021): 26–29. https://doi.org/10.1016/j.prro.2020.11.004.

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Hoffe, S., J. M. Frakes, T. A. Aguilera, B. Czito, M. Palta, M. Brookes, C. Schweizer, et al. “Randomized, Double-Blinded, Placebo-controlled Multicenter Adaptive Phase 1-2 Trial of GC 4419, a Dismutase Mimetic, in Combination with High Dose Stereotactic Body Radiation Therapy (SBRT) in Locally Advanced Pancreatic Cancer (PC).” In Int J Radiat Oncol Biol Phys, 108:1399–1400, 2020. https://doi.org/10.1016/j.ijrobp.2020.09.022.

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Song, Erin J., Corbin D. Jacobs, Manisha Palta, Christopher G. Willett, Yuan Wu, and Brian G. Czito. “Evaluating treatment protocols for rectal squamous cell carcinomas: the Duke experience and literature.” J Gastrointest Oncol 11, no. 2 (April 2020): 242–49. https://doi.org/10.21037/jgo.2018.11.02.

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Xiao, Linlin, Brian G. Czito, Qingsong Pang, Zhouguang Hui, Shaowu Jing, Baoen Shan, and Jun Wang. “Do Higher Radiation Doses with Concurrent Chemotherapy in the Definitive Treatment of Esophageal Cancer Improve Outcomes? A Meta-Analysis and Systematic Review.” Journal of Cancer 11, no. 15 (January 2020): 4605–13. https://doi.org/10.7150/jca.44447.

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Jacobs, Corbin D., Jacob Trotter, Manisha Palta, Michael J. Moravan, Yuan Wu, Christopher G. Willett, W Robert Lee, and Brian G. Czito. “Multi-Institutional Analysis of Synchronous Prostate and Rectosigmoid Cancers.” Front Oncol 10 (2020): 345. https://doi.org/10.3389/fonc.2020.00345.

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Jing, Shao-Wu, Jian-Jun Qin, Qing Liu, Chang Zhai, Ya-Jing Wu, Yun-Jie Cheng, Brian G. Czito, and Jun Wang. “Comparison of neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy for esophageal cancer: a meta-analysis.” Future Oncol 15, no. 20 (July 2019): 2413–22. https://doi.org/10.2217/fon-2019-0024.

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Abdelazim, Yasser A., Christel N. Rushing, Manisha Palta, Christopher G. Willett, and Brian G. Czito. “Role of pelvic chemoradiation therapy in patients with initially metastatic anal canal cancer: A National Cancer Database review.” Cancer 125, no. 12 (June 15, 2019): 2115–22. https://doi.org/10.1002/cncr.32017.

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Ji, Keven S. Y., Samantha M. Thomas, Sanziana A. Roman, Brian Czito, Kevin L. Anderson, Jessica Frakes, Mohamed A. Adam, Julie A. Sosa, and Timothy J. Robinson. “Low- vs. High-Dose Neoadjuvant Radiation in Trimodality Treatment of Locally Advanced Esophageal Cancer.” J Gastrointest Surg 23, no. 5 (May 2019): 885–94. https://doi.org/10.1007/s11605-018-4007-3.

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