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John P. Kirkpatrick, MD, PhD

Professor of Radiation Oncology
Professor in Neurosurgery
Office: Department of Radiation Oncology, Durham, NC 27710
Campus Mail: DUMC DUMC Box 3085, Durham, NC 27710

Malignant and benign tumors of the brain, spine and base of skull. Mathematical modelling of tumor metabolism, mass transfer and the response to ionizing radiation. Enhancing clinical outcome in stereotactic radiosurgery, fractionated stereotactic radiotherapy and stereotactic body radiotherapy.

Education and Training

  • M.D., University of Texas Health Science Center San Antonio, 1999
  • Ph.D., Rice University, 1978

Publications

Lee, Jessica W., John P. Kirkpatrick, Frances McSherry, James E. Herndon, Eric S. Lipp, Annick Desjardins, Dina M. Randazzo, et al. “Adjuvant Radiation in Older Patients With Glioblastoma: A Retrospective Single Institution Analysis.” Front Oncol 11 (2021): 631618. https://doi.org/10.3389/fonc.2021.631618.

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Soltys, Scott G., Michael T. Milano, Jinyu Xue, Wolfgang A. Tomé, Ellen Yorke, Jason Sheehan, George X. Ding, et al. “Stereotactic Radiosurgery for Vestibular Schwannomas: Tumor Control Probability Analyses and Recommended Reporting Standards.” Int J Radiat Oncol Biol Phys, December 26, 2020. https://doi.org/10.1016/j.ijrobp.2020.11.019.

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Sperduto, Paul W., Shane Mesko, Jing Li, Daniel Cagney, Ayal Aizer, Nancy U. Lin, Eric Nesbit, et al. “Survival in Patients With Brain Metastases: Summary Report on the Updated Diagnosis-Specific Graded Prognostic Assessment and Definition of the Eligibility Quotient.” J Clin Oncol 38, no. 32 (November 10, 2020): 3773–84. https://doi.org/10.1200/JCO.20.01255.

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Park, Christine, Elizabeth P. Howell, Vikram A. Mehta, Luis Ramirez, Meghan J. Price, Scott R. Floyd, John P. Kirkpatrick, et al. “Patient outcomes and tumor control in single-fraction versus hypofractionated stereotactic body radiation therapy for spinal metastases.” J Neurosurg Spine, November 6, 2020, 1–10. https://doi.org/10.3171/2020.6.SPINE20349.

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Sperduto, Paul W., Shane Mesko, Jing Li, Daniel Cagney, Ayal Aizer, Nancy U. Lin, Eric Nesbit, et al. “Estrogen/progesterone receptor and HER2 discordance between primary tumor and brain metastases in breast cancer and its effect on treatment and survival.” Neuro Oncol 22, no. 9 (September 29, 2020): 1359–67. https://doi.org/10.1093/neuonc/noaa025.

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Dial, Brian L., Anthony A. Catanzano, Valentine Esposito, John Steele, Amanda Fletcher, Sean P. Ryan, John P. Kirkpatrick, et al. “Treatment Outcomes in Spinal Metastatic Disease With Indeterminate Stability.” Global Spine J, September 25, 2020, 2192568220956605. https://doi.org/10.1177/2192568220956605.

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Lee, J. W. C., M. O. Johnson, J. P. Kirkpatrick, F. McSherry, J. Herndon, E. S. Lipp, A. Desjardins, et al. “Outcomes Following Adjuvant Radiation Therapy in Elderly Patients with Glioblastoma: A Retrospective Single Institution Analysis.” In International Journal of Radiation Oncology*Biology*Physics, 105:E102–E102. Elsevier BV, 2020. https://doi.org/10.1016/j.ijrobp.2019.06.2296.

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Sperduto, Paul W., Shane Mesko, Jing Li, Daniel Cagney, Ayal Aizer, Nancy U. Lin, Eric Nesbit, et al. “Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today.” Int J Radiat Oncol Biol Phys 107, no. 2 (June 1, 2020): 334–43. https://doi.org/10.1016/j.ijrobp.2020.01.051.

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Cui, Yunfeng, Hao Gao, Jiahan Zhang, John P. Kirkpatrick, and Fang-Fang Yin. “Retrospective quality metrics review of stereotactic radiosurgery plans treating multiple targets using single-isocenter volumetric modulated arc therapy.” J Appl Clin Med Phys 21, no. 6 (June 2020): 93–99. https://doi.org/10.1002/acm2.12869.

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Moravan, Michael J., Peter E. Fecci, Carey K. Anders, Jeffrey M. Clarke, April K. S. Salama, Justus D. Adamson, Scott R. Floyd, et al. “Current multidisciplinary management of brain metastases.” Cancer 126, no. 7 (April 1, 2020): 1390–1406. https://doi.org/10.1002/cncr.32714.

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