Featured publications:

  1. Lee CL*, Moding EJ*, Huang X, Li Y, Woodlief LZ, Rodrigues RC, Ma Y, Kirsch DG. Generation of Primary Tumors with Flp Recombinase in FRT-flanked p53 Mice. Disease, Models, and Mechanisms. 2012 May; 5(3):397-402. PMCID: PMC3339833 (*Equal contribution)

  2. Lee CL, Moding EJ, Cuneo KC, Li Y, Sullivan JM, Mao L, Washington I, Jeffords LB, Rodrigues RC, Ma Y, Das S, Kontos CD, Kim Y, Rockman HA, Kirsch DGp53 Functions in Endothelial Cells to Prevent Radiation-Induced Myocardial Injury in Mice. Science Signaling. 2012 Jul 24; 5(234). PMCID: PMC3533440

  3. Lee CL, Blum JM, Kirsch DG. Role of p53 in Regulating Tissue Response to Radiation by Mechanisms Independent of Apoptosis. Translational Cancer Research. 2013 Oct; 2(5):412-421. PMCID: PMC3898670

  4. Lee CL, Min H, Befera N, Clark D, Qi Y, Das S, Johnson GA, Badea CT, Kirsch DG. Assessing Cardiac Injury in Mice with Dual Energy-microCT, 4D-microCT, and microSPECT Imaging After Partial Heart Irradiation. International Journal of Radiation Oncology, Biology, Physics. 2014 Mar 1;88(3):686-693. PMCID: PMC3985387 

  5. Lee CL*, Lento WE*, Castle KD, Chao NJ, Kirsch DG. Inhibiting Glycogen Synthase Kinase-3 Mitigates the Hematopoietic Acute Radiation Syndrome in Mice. Radiation Research. 2014 May; 181(5):445-451. PMCID: PMC4080719 (*Equal contribution)

  6. Moding EJ, Lee CL, Castle KD, Oh P, Mao L, Zha S, Min HD, Ma Y, Das S, Kirsch DG. ATM Deletion with Dual Recombinase Technology Preferentially Radiosensitizes Tumor Endothelium. Journal of Clinical Investigation. 2014 Aug 1; 124(8):3325-38. PMCID: PMC4109553

  7. Lee CL, Castle KD, Moding EJ, Blum JM, Williams N, Luo L, Ma Y, Borst L, Kim Y, Kirsch DG. Acute DNA Damage Activates the Tumor Suppressor p53 to Promote Radiation-induced Lymphoma. Nature Communications. 2015 Sep 24;6:8477. PMCID: PMC4586051

  8. Moding EJ, Min HD, Castle KD, Ali M, Woodlief L, Williams N, Ma Y, Kim Y, Lee CL, Kirsch DG. An Extra Copy of p53 Suppresses Development of Spontaneous Kras-driven but not Radiation-Induced Cancer. JCI Insight. 2016 Jul 7;1(10). pii:e86698. PMCID:PMC4955525

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